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Hamaguchi Lab.
濵口研究室

― 物質と生命をつなぐ分光物理化学 ―

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濵口宏夫教授


学歴および職歴

生年月日: 1947年9月21日 (東京都)

1970年 東京大学理学部化学科卒業
1970年 東京大学大学院理学系研究科化学専攻入学
1975年 同博士課程修了(理学博士)
1975年 東京大学理学部助手
1981年 東京大学理学部講師
1983年 東京大学理学部助教授
1990年 神奈川科学技術アカデミー研究室長
1995年 東京大学教養学部教授
1997年 東京大学大学院理学系研究科化学専攻物理化学講座教授
2007年 台湾国立交通大学理学院講座教授

学会等における活動

  1. 国際学術誌
    • Chemical Physics Letters (Elsevier), Editorial Advisory Board (1988-present).
    • Bulletin of the Chemical Society of Japan, 編集委員 (1988-1990).
    • Laser Chemistry (Gordon&Bleach), Editorial Advisory Board (1992-present).
    • Chemical Physics (Elsevier), Editorial Advisory Board (1992-present).
    • Journal of Raman Spectroscopy (Wiley), Associate Editor (1997-present).
    • Chemistry Letters, 編集委員 (1997-2000).
    • Applied Spectroscopy, Associate Editor for Japan (2000-2009).
    • Journal of Molecular Structure (Elsevier), Editorial Advisory Board (2004-present).
  2. 国際会議
    • The KAST International Symposium on Time-resolved Spectroscopy (Kawasaki, 1991) Organizer.
    • The 10th International Conference on Time-resolved Vibrational Spectroscopy (Okazaki, 2001) Co-chair.
    • The 20th International Conference on Raman Spectroscopy (Yokohama, 2006) Chair.
    • The 2nd International Congress on Ionic liquids (Yokohama, 2007) Co-Chair.
    • Advanced Spectroscopy and Imaging in Molecular Science (Hsinchu, Taiwan, 2010) Co-chair.
  3. 国際学会等役員
    • International Conference on Time-resolved Vibrational Spectroscopy
    • Laser Applications in Life Sciences
    • International Conference on Raman Spectroscopy (2006-present, Steering Committee Chairman 2008-2010)
    • Asian Conference on Spectroscopy(2007-present, Steering Committee Founding Chairman)
    • European Congress on Molecular Spectroscopy(2008-present)
    • CODATA Executive Committee member (2010-present)
  4. 国内学会等役員
    • 日本分光学会赤外・ラマン研究部会幹事 (1983-1985)
    • 日本化学会「化学と工業」編集委員 (1984-1986)
    • 日本分光学会赤外・ラマン研究部会主査 (1985-1987)
    • 日本分光学会常務理事 (1987-1989)
    • 日本化学会Bulletin of the Chemical Society of Japan編集委員 (1988-1990)
    • 日本分光学会評議員 (1989-1991)
    • 日本化学会Chemistry Letters編集委員 (1997-2000)
    • 日本化学会理事 (2000-2002)
    • 分子構造総合討論会運営委員会代表幹事 (2002-2004)
    • 日本分光学会会長 (2003-2005)
    • イオン液体研究会代表世話人 (2004-現在)
    • 医用分光学研究会代表世話人 (2004-2009)
    • 日本工業規格ラマン分光分析法通則委員会委員長(2008-2009)
    • 日本分光学会評議員 (2006-現在)
    • 日本分光学会推薦委員会委員長 (2008-2009)
    • (財)井上科学振興財団評議員 (2010-)

受賞、レクチャーシップなど

  • Ramasay Fellow (1977-1979年)
  • Pittzburgh Conrerence Lectures (1993年)
  • Meggers Award (2005年)
  • 日本分光学会賞 (2006年)
  • 日本化学会賞 (2009年)
  • TRVS (Time-resolved Vibrational Spectroscopy) Award (2009年)
  • Fellow of the Society for Applied Spectroscopy USA (2010年)

国内学会、国際会議等での招待講演 (2009年度以降)

  1. Deca-second Mitochondria Dynamics of Living Yeast Cells as Studied by Time- and Space-resolved Raman Spectroscopy.
    M. Kato, C. Onogi, H. Hamaguchi,
    The 22nd International Conference on Raman Spectroscopy, Boston (2010.8).
  2. Recent Developments in Space-resolved Raman Spectroscopy at Tokyo: Single Molecules, Nano-structures and Single Living Cells.
    Hiro-o Hamaguchi,
    Gordon Research Conference on Vibrational Spectroscopy, Bidderford, USA (2010.8)
  3. Raman and CARS: Which wins in microspectroscopy of living cells?
    Hiro-o Hamaguchi,
    European Conference on Non-linear Optics and Spectroscopy, Bremen (2010.6)
  4. What Are Local Structures and Micro Molecular Environments in Ionic Liquids?
    Hiro-o Hamaguchi,
    ACS Symposium, San Francisco (2010.3).
  5. Raman Spectroscopic View of Life.
    Hiro-o Hamaguchi,
    Indian Academy of Science Platinum Jubilee Meeting, Bangalore (2009.11).
  6. Living Cell Chemistry: Looking at Life with Chemical Eyes.
    Hiro-o Hamaguchi,
    Topical Problems in Biophotonics 2009, Nizhny Novgorod (2009.7).
  7. Nanoscopic Structure of Ionic Liquids.
    Hiro-o Hamaguchi,
    3rd International Congress on Ionic Liquids, Cairns (2009.6).
  8. Toward Single Molecule and Single Cell Time-resolved Vibrational Spectroscopy.
    Hiro-o Hamaguchi,
    14th International Conference on Time-resolved Vibrational Spectroscopy, Meredith NH, USA (2009.5).
  9. Can Raman Spectroscopy Image Life?
    Hiro-o Hamaguchi,
    9th National Institute for Basic Biology Symposium, Okazaki (2009.4).
  10. Can Raman Spectroscopy Measure and Quantify Life?
    Hiro-o Hamaguchi,
    Physics of Qunatum Electronics Conference 2009, Snowbird (2009.1).
  11. 線型および非線型ラマン顕微分光による酵母生細胞の分子イメージング.
    濵口宏夫,
    2006 応用物理学会シンポジウム,京都 (2006.8)
  12. 「生命のラマン分光指標」と分子レベルでの細胞死.
    濵口宏夫,
    2006 生体分子科学討論会,名古屋 (2006.7)
  13. イオン液体のナノ構造とナノ環境.
    濵口宏夫,
    第4回ナノ学会,京都 (2006.6)
  14. ラマン分光による単一酵母生細胞の分子レベル分光と生物活性の可視化.
    濵口宏夫,
    酵母合同シンポジウム,甲府 (2006.6)
  15. 新しい振動分光学的手法の開発と応用.
    濵口宏夫,
    日本分光学会春季講演会,東京 (2006.5)
  16. 時空間分解振動分光学-反応中間体から生細胞まで-
    濵口宏夫,
    JCII講演会,東京 (2006.5)

発表論文 (2009年度以降)

  1. Protein Secondary Structure Imaging with Ultrabroadband Multiplex Coherent Anti-Stokes Raman Scattering (CARS) Microspectroscopy.
    Kotatsu Bito, Masanari Okuno, Hideaki Kano, Shihomi Tokuhara, Satoru Naito, Yoshinori Masukawa, Philippe Leproux, Vincent Couderc and Hiro-o Hamaguchi,
    J. Phys. Chem. B. , Accepted (2012).
  2. Two-step photoionization of trans-stilbene in acetonitrile via an ion-pair precursor studied with picosecond time-resolved absorption and Raman spectroscopies.
    Hiroko Miki, Kyousuke Yoshida, Chieko Kawate, Rintaro Shimada, Tomohisa Takaya, Koichi Iwata and Hiro-o Hamaguchi,
    Chem. Phys. Lett. , Accepted (2012).
  3. Rotational dynamics of solvated carbon dioxide studied by infrared, Raman, and time-resolved infrared spectroscopies and a molecular dynamics simulation.
    Kaori Watanabe, Hajime Okajima, Takuya Kato, and Hiro-o Hamaguchi,
    J. Chem. Phys., 136, 014508 (2012).
  4. Resonance Raman quantification of the redox state of cytochromes b and c in-vivo and in-vitro.
    Minoru Kakita, Venkatesh Kaliaperumal and Hiro-o Hamaguchi,
    J. Biophoton., 5, 20-24 (2012).
  5. Unusually long trans/gauche conformational equilibration time during the melting process of BmimCl, a prototype ionic liquid.
    Hajime Okajima and Hiro-o Hamaguchi,
    Chem. Lett., 40, 1308-1309 (2011).
  6. In vivo multimode Raman imaging reveals concerted molecular composition and distribution changes during yeast cell cycle.
    Chuan-Keng Huang, Hiro-o Hamaguchi and Shinsuke Shigeto,
    Chem. Comm., 47, 9423-9425 (2011).
  7. New opportunities offered by compact sub-nanosecond supercontinuum sources in ultrabroadband multiplex CARS microspectroscopy.
    Philippe Leproux, Vincent Couderc, Annalisa De Angelis, Masanari Okuno, Hideaki Kano and Hiro-o Hamaguchi,
    J. Raman spectrosc., 42, 1871-1874 (2011).
  8. Superresolution vibrational imaging by simultaneous detection of Raman and hyper-Raman scattering.
    Korenobu Matsuzaki, Rintaro Shimada and Hiro-o Hamaguchi,
    Opt. Lett., 36, 2545-2547 (2011).
  9. Quantitative Coherent Anti-Stokes Raman Scattering (CARS) Microscopy.
    James P. R. Day, Katrin F. Domke, Gianluca Rago, Hideaki Kano, Hiro-o Hamaguchi, Erik M. Vartiainen, and Mischa Bonn,
    J. Phys. Chem. B, 115, 7713-7725 (2011).
  10. 1064 nm deep near-infrared (NIR) excited Raman microspectroscopy for studying photolabile organisms.
    Masahiro Ando, Miwa Sugiura, Hidenori Hayashi, and Hiro-o Hamaguchi,
    Appl. Spectrosc., 65, 488-492 (2011).
  11. The “Raman spectroscopic signature of life” is closely related to haem function in budding yeasts.
    Liang-da Chiu and Hiro-o Hamaguchi,
    J. Biophoton., 4, 30-33 (2011).
  12. Solute-solvent intermolecular vibronic coupling as manifested by the molecular near-field effect in resonance hyper-Raman scattering.
    Rintaro Shimada and Hiro-o Hamaguchi,
    J. Chem. Phys., 134, 034516 (2011).
  13. Multifocus confocal Raman microspectroscopy for fast multimode vibrational imaging of living cells.
    Masanari Okuno and Hiro-o Hamaguchi,
    Opt. Lett., 35, 4096-4098 (2010).
  14. Ordering, interaction, and reactivity of the low-lying nπ* and ππ* excited triplet states of acetophenone derivatives.
    Sohshi Yabumoto, Shinsuke Shigeto, Yuan-Pern Lee and Hiro-o Hamaguchi
    Angew. Chem. Int. Ed., 49, 9201-9205 (2010).
  15. Differentiation of animal fats from different origins: use of polymorphic features detected by Raman spectroscopy.
    Michiyo Motoyama, Masahiro Ando, Keisuke Sasaki, and Hiro-o Hamaguchi,
    Appl. Spectrosc., 64, 1244-1250 (2010).
  16. Quantitative CARS molecular fingerprinting of single living cells with the use of the maximum entropy method.
    Masanari Okuno, Hideaki Kano, Philippe Leproux, Vincent Couderc, James P. R. Day, Mischa Bonn and Hiro-o Hamaguchi,
    Angew. Chem. Int. Ed., 49, 6773-6777 (2010).
  17. Triplet quantum chain process in the photoisomerization of 9-cis retinal as revealed by nanosecond time-resolved infrared spectroscopy.
    Tetsuro Yuzawa and Hiro-o Hamaguchi,
    J. Mol. Struc., 976, 414-418 (2010).
  18. In vivo resonance raman detection of ferrous cytochrome c from mitochondria of single living yeast cells.
    Chikao Onogi and Hiro-o Hamaguchi,
    Chem. Lett. , 39, 270-271 (2010).
  19. Visible nonlinear band-edge luminescence in ZnSe and CdS excited by a mid-infrared free-electron laser.
    Eiji Tokunaga, Naoto Sato, Jiro Korenaga, Takayuki Imai, Shin Sato and Hiro-o Hamaguchi,
    Opt. Rev. , 17, 341-345 (2010).
  20. Two different charge transfer states of photoexcited 9,9′-bianthryl in polar and nonpolar solvents characterized by nanosecond time-resolved near-IR spectroscopy in the 4500-10500 cm?1 region.
    Nobuyuki Asami, Tomohisa Takaya, Soshi Yabumoto, Shinsuke Shigeto, Hiro-o Hamaguchi and Koichi Iwata ,
    J. Phys. Chem. A , 114, 6351-6365 (2010).
  21. A near-infrared Raman spectroscopic study on the bovine lens applied to the solar radiation in Antarctica.
    Tatsuyuki Yamamoto, Keisuke Yoshikiyo, Young-Kun Min, Hiro-o Hamaguchi, Satoshi Imura, Sakae Kudoh, Tetsuya Takahashi and Naoyuki Yamamoto,
    J. Mol. Struct. , 968, 115-119 (2010).
  22. Study of the ‘Raman spectroscopic signature of life’ in mitochondria isolated from budding yeast.
    Liang-da Chiu, Masahiro Ando and Hiro-o Hamaguchi,
    J. Raman Spectrosc. , 41, 2-3 (2010).
  23. Raman spectra of isotope-substituted mitochondria of living budding yeast cells: possible origin of the "Raman spectroscopic signature of life".
    Chikao Onogi, Hajime Torii and Hiro-o Hamaguchi,
    Chem. Lett., 38, 898-890 (2009).
  24. Fast low frequency (down to 10 cm-1) multichannel Raman spectroscopy using an iodine vapor filter.
    Hajime Okajima and Hiro-o Hamaguchi,
    Appl. Spectrosc. , 63, 958-960 (2009).
  25. Photobleaching of the "Raman spectroscopic signature of life" and mitochondrial activity in rho- budding yeast cells.
    Chikao Onogi and Hiro-o Hamaguchi,
    J. Phys. Chem. B , 113, 10942-10945 (2009).
  26. Femtosecond time-resolved absorption anisotropy spectroscopy on 9,9'-bianthryl: Detection of partial intramolecular charge transfer in polar and nonpolar solvents.
    Tomohisa Takaya, Hiro-o Hamaguchi and Koichi Iwata,
    J. Chem. Phys., 130, 14501 (2009).
  27. Intermolecular interaction between W(CO)6 and alkane molecules probed by ultrafast vibrational energy relaxation: anomalously strong interaction between W(CO)6 and decane.
    Motohiro Banno, Koichi Iwata and Hiro-o Hamaguchi,
    J. Phys. Chem. A , 113, 1007-1011 (2009).
  28. Developments of Raman spectroscopy in the past 40 years: from a molecule to a living cell.
    Hiro-o Hamaguchi,
    Curr. Sci. , 97, 186-191 (2009).
  29. Ultrafast Protonation/Deprotonation Dynamics of N,N-Dimethylacetamide in Hydrochloric Acid As Studied by Raman Band Shape Analysis.
    Daisuke Watanabe and Hiro-o Hamaguchi,
    J. Phys. Chem. C , 27, 11662-11666 (2009).

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